January 2022 Test Bulletin

January 14, 2022

In this bulletin, Alverno Laboratories provided important updates for healthcare providers. Firstly, they highlighted the potential for false reactive results on the RPR non-Treponemal Syphilis screen within 5 months of mRNA COVID-19 vaccination, advising careful interpretation in conjunction with patient history and risk factors. They also outlined two testing algorithms for Syphilis screening: the traditional RPR first approach and the reverse Treponemal antibody first strategy, with confirmatory testing following the initial screen assay. Secondly, they noted a correction regarding the postponement of updates for CBC pediatric ranges and manual differential reference range to April 2022, previously mentioned in a client bulletin. These updates aim to ensure accurate testing and interpretation, particularly in light of evolving clinical contexts.