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Alverno Laboratories
Clinical Test Bulletins

Dear Healthcare Provider,
The information contained here may be very important to your practice. Please take a moment to review this document.

DRUG SCREEN PANEL UPDATES

February, 2020

Alverno Laboratories is pleased to announce an update to and consolidation of our Drug of Abuse screening panels. The new panels will be offered with or without confirmation. All previous panels will be discontinued except for the Occupational Medicine drug screen panels and drug screen panels performed at the local hospital sites. Please see page 2 through 4 for details.

LUPUS ANTICOAGULANT AND ANTI-PHOSPHOLIPID SYNDROME PANELS

February 4, 2020

Effective February 4, 2020, Alverno will resume Lupus Anticoagulant Reflexive Panel testing in-house and offer an additional Anti-Phospholipid Syndrome Panel. Please see page 5 for details.

PAIN MANAGEMENT PANEL UPDATE

February 18, 2020

Alverno Laboratories is pleased to announce Pain Management Panel testing will now be conducted in-house on our Liquid Chromatography Mass Spectrometer (LCMS), reducing turnaround time. Alverno’s Pain Management Panel will be more comprehensive, consisting of 79 reported analytes, specimen validity, and an interpretation based on the submitted medication list. Please see page 6 through 9 for details.

Test Summary

Drug Screen Panel Updates

February 2020

Alverno Laboratories is pleased to announce an update to and consolidation of our Drug of Abuse screening panels. The new panels will be offered with or without confirmation. All previous panels will be discontinued except for the Occupational Medicine drug screen panels and drug screen panels performed at the local hospital sites. The Occ Med Panels will now come with confirmatory testing. Please note that Propoxyphene has been removed from the new panels however will be offered as an individual screening test if needed. Please see the table below of newly offered screening options.

Specimen Requirements

Specimen: Urine, 5mL (min)
Stability: Up to 5 days refrigerated
Method: EIA
Availability: Testing is available 24 hours a day, 7 days a week
CPT: 80307*

Information regarding Soft order codes and CPT codes* can be found on our website, or by calling 800-937-5521.

*CPT codes provided are for informational purposes only. Questions regarding coding should be directed to the payer.

Lupus Anticoagulant and Anti-Phospholipid Syndrome Panels

February 4, 2020

Effective February 4, 2020, Alverno will resume Lupus Anticoagulant Reflexive Panel testing in-house and offer an additional Anti-Phospholipid Syndrome Panel. The Alverno Lupus Anticoagulant Reflexive panel will utilize the Clinical and Laboratory Standards Institute (CLSI) 2014 guidelines for Lupus Anticoagulant identification and will include prescreening tests, the lupus anticoagulant screening assays, mixing studies if indicated, and a pathologist interpretation of results. The Anti-Phospholipid Syndrome panel will include β2-Glycoprotein antibodies IgG and IgM, and Cardiolipin antibodies IgG and IgM in addition to the Lupus Reflexive Panel testing. The inclusion of prescreening tests and mixing studies will help to detect if coagulation results are prolonged due to a lupus anticoagulant, a factor deficiency, direct oral anticoagulant interference, a vitamin K antagonist, or other inhibitors.

Due to the comprehensive nature of the test, it is imperative that the full amount of required specimen (as per the phlebotomy label) be sent to the Central Lab for processing. Please see updated specifications below.

Pain Management Panel Update

February 18, 2020

Alverno Laboratories is pleased to announce Pain Management Panel testing will now be conducted in-house on our Liquid Chromatography Mass Spectrometer (LCMS) reducing turnaround time. Alverno’s Pain Management Panel will be more comprehensive, consisting of 79 reported analytes, specimen validity, and an interpretation based on the submitted medication list. Specimen validity will be evaluated via pH testing, creatinine analysis and specific gravity. The table below provides more detail of the new panel’s analytes and cutoffs, as well as a comparison to the current panel provided by ARUP. At this time, samples will be batched on Tuesday and Thursday, with the interpretations being completed on Wednesday and Friday. Alverno will provide a new report template, creating a more user-friendly report. Analytes will now be reported with quantitation.

Specimen Requirements

Specimen: Urine, 10mL
Stability: Up to 7 days refrigerated
Method: Liquid Chromatography Mass Spectrometry
Availability: Batched; Tuesday and Thursday
CPT: 80307*

Information regarding Soft order codes and CPT codes* can be found on our website, or by calling 800-937-5521.

*CPT codes provided are for informational purposes only. Questions regarding coding should be directed to the payer.